Dapoxetine: Fast Facts and Practical Guide

Premature ejaculation affects about one in three men at some point. Dapoxetine is a short-acting selective serotonin reuptake inhibitor designed specifically for this problem. You take it only when needed before sex, not every day. It raises serotonin briefly to delay ejaculation and usually works within one to three hours.

How to use dapoxetine Side effects and safety notes

Typical starting dose is 30 mg taken one to three hours before sexual activity. If 30 mg doesn’t help after a few tries, a doctor may increase the dose to 60 mg. Do not take more than one dose in 24 hours. Dapoxetine is for adult men only; it is not approved for children or women. Read the leaflet for dose adjustments if you have liver problems and ask your doctor if you have kidney disease.

Common side effects include nausea, headache, dizziness, diarrhea and insomnia. Because dapoxetine can lower blood pressure and cause fainting, avoid rapid standing and use caution if you drink alcohol. Don’t combine dapoxetine with monoamine oxidase inhibitors (MAOIs), other SSRIs, tramadol, or strong CYP3A4 inhibitors like ketoconazole without medical advice. Mixing serotonergic drugs raises the risk of serotonin syndrome, which needs urgent care. People with a history of heart rhythm problems, low blood pressure, or seizures should not use dapoxetine.

Buying dapoxetine: what to watch for Alternatives and practical tips Talking to your doctor

In many countries dapoxetine requires a prescription. Online pharmacies that ask for no prescription are risky. If buying online, choose a pharmacy that shows verification, a licensed pharmacist contact, and clear return policies. Avoid pills that are much cheaper than usual or arrive in unbranded packaging. Telemedicine services that include a doctor consultation and prescription are a safer option for remote purchases.

If dapoxetine isn’t suitable, talk with your doctor about alternatives: topical anesthetic creams, daily SSRIs used off-label, behavioral techniques like the squeeze or stop-start method, or counseling for anxiety. Sometimes combining drug treatment with therapy gives the best long-term result. Track how often side effects happen and discuss any serious symptoms immediately.

Be direct: describe how often premature ejaculation happens, how it affects your sex life, and any other medicines you take. Bring a list of alcohol use, heart conditions, and past seizures. A clear medical history helps your doctor decide whether dapoxetine is a safe, effective choice.

If you need help finding a verified online pharmacy or want a checklist to discuss with your clinician, ClearSkyPharmacy.Biz has guides and trusted resources to help you make a safe plan.

If you experience severe dizziness, fainting, chest pain, irregular heartbeat, or signs of serotonin syndrome (high fever, rapid heartbeat, confusion, muscle stiffness), stop the medication and seek emergency care. Report common side effects to your prescriber; many lessen after a few doses. Store dapoxetine at room temperature away from moisture. Keep pills in original packaging and don’t share them. If a dose is missed, skip it—do not double up the next day. Talk with partners.