Lurasidone (Latuda): What It Treats and How It Works

Lurasidone, often known by the brand name Latuda, is an antipsychotic used mainly for schizophrenia and bipolar depression. It acts on dopamine and serotonin receptors in the brain to help reduce symptoms like delusions, hallucinations, low mood, and agitation. If you or someone you care for is starting lurasidone, knowing the basics—how to take it, what to expect, and what to watch for—makes a real difference.

How to take lurasidone

Take lurasidone exactly as your doctor prescribes. A key point: take it with food. Lurasidone needs a meal of about 350 calories to absorb properly, so avoid taking it on an empty stomach. Doctors commonly start adults at a low daily dose and adjust based on response and side effects; many patients begin at 40 mg once daily for schizophrenia, while bipolar depression dosing is usually lower. Don’t split tablets unless your pharmacist says it’s safe. If you miss a dose, take it as soon as you remember the same day; skip it if it's near your next dose—don’t double up.

Side effects, risks, and what to watch for

Common side effects include drowsiness, nausea, restlessness (akathisia), and sometimes mild weight gain. Some people experience movement issues—shaky limbs or stiffness—so report involuntary movements to your clinician right away. Lurasidone can affect blood sugar, cholesterol, and weight, so routine monitoring (weight checks, blood sugar and lipid tests) is often recommended.

There are a few serious safety notes: antipsychotics can increase the risk of death in older adults with dementia-related psychosis. Also be cautious if you have a history of heart problems, low blood pressure, or seizures—tell your doctor. Pregnant or breastfeeding? Talk to your provider before starting or stopping lurasidone.

Drug interactions matter. Lurasidone is processed by CYP3A4 in the liver. Strong CYP3A4 inhibitors (like ketoconazole) or inducers (like rifampin) can change lurasidone levels and cause harm. Always tell your prescriber about other meds, supplements, or herbal products you use. Avoid heavy drinking while on antipsychotics.

If you feel worse, have suicidal thoughts, or notice sudden movement problems, seek medical help immediately. For milder side effects, your doctor may adjust the dose or try a different medication.

Buying lurasidone: never order prescription meds without a valid prescription. Use licensed pharmacies, check pharmacist credentials, and avoid sites offering big discounts without asking for a prescription. If you shop online, prefer pharmacies with clear contact info, pharmacy licenses, and secure payment. Your health isn’t worth a gamble.

Want more detailed articles on safe online pharmacies, medication alternatives, and practical tips for buying meds? Our site covers buying safely, comparing options, and what to ask your clinician so you get treatment that actually fits your needs.