Tadalafil: What It Is and How People Use It

Tadalafil is a medicine most people know for treating erectile dysfunction (ED). You might also see it used for benign prostatic hyperplasia (BPH) and pulmonary arterial hypertension under different brand names. It’s popular because one dose can work for many hours, so couples often like the flexibility. But before you try it, a few clear facts help you stay safe and get the effect you want.

How tadalafil works and how to take it

Tadalafil relaxes blood vessels and improves blood flow to certain parts of the body. For ED, that means better blood flow to the penis when you’re sexually aroused. Typical “as-needed” doses are 5 mg, 10 mg, or 20 mg taken about 30–60 minutes before sex. There’s also a daily low-dose option—usually 2.5 mg or 5 mg—if you want more spontaneous activity without timing a pill. The big practical benefit: effects can last up to 36 hours in many people, so it’s often called the "weekend pill."

Start low and talk to your doctor about the right dose. If you’re on other medications, especially blood pressure drugs, your doctor will pick a safer option. Don’t increase the dose on your own if one tablet didn’t work—check with a clinician first.

Side effects, interactions, and safety tips

Common side effects include headache, flushing, indigestion, back pain, and muscle aches. These usually fade in a day or two. The serious risk is a dangerous drop in blood pressure when tadalafil is taken with nitrates (medicines often used for chest pain). If you use nitrates, do not take tadalafil. Also be cautious with alpha-blockers, some blood pressure medicines, and certain antifungals or antibiotics that change how your body processes tadalafil.

If you get sudden vision loss, hearing loss, or an erection lasting longer than four hours (priapism), get emergency help. Those are rare but need immediate attention. Also mention heart disease or stroke history to your prescriber—sexual activity can strain the heart.

Buying tips: always use a licensed pharmacy and keep your prescription. Avoid sites that sell without a prescription, offer suspiciously low prices, or won’t provide clear contact details. Look for pharmacy verification seals and readable pharmacist contact info. If a tablet looks off in color or shape, don’t take it. Finally, check expiry dates and storage instructions—tadalafil stores fine at room temperature away from moisture.

Want to try tadalafil? Talk to your doctor or a trusted telehealth provider. They can check interactions, pick a dose, and discuss lifestyle steps that often improve ED—like quitting smoking, cutting back on alcohol, and managing weight. A short chat can make sure tadalafil helps you safely and effectively.